Kidney problems after Clopidogrel in dogs

25 reports to the FDA describe kidney problems in dogs given Clopidogrel. That is 25% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

25Reports
84%Marked serious
4.0%Recovered
64%Died or euthanised
34 daysTypical onset
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How soon it started

Same day
2 10%
1–2 days
1 5.0%
3–7 days
3 15%
1–4 weeks
4 20%
Over a month
10 50%

How the animals did

Recovered
1 4.0%
Still unwell when reported
4 16%
Died
5 20%
Euthanised
11 44%
Not known
4 16%

Problems reported at the same time

16 64%
12 48%
Proteinuria
11 44%
11 44%
Leucocytosis
7 28%

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
2
8–11 years
14
12+ years
7

About this medicine

Type: medicine.

Questions owners ask

Can Clopidogrel cause kidney problems in dogs?
25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 34 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Clopidogrel in dogs · Medicines most reported with kidney problems