Lymphadenopathy after Cefpodoxime in dogs

The FDA has received 28 reports of lymphadenopathy in dogs after Cefpodoxime. That is 0.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

28Reports

32%Marked serious

7.1%Recovered

29%Died or euthanised

10 daysTypical onset

How soon it started

Same day

1 7.1%

1–2 days

2 14%

3–7 days

4 29%

1–4 weeks

2 14%

Over a month

5 36%

How the animals did

Recovered

2 7.1%

Still unwell when reported

8 29%

Died

4 14%

Euthanised

4 14%

Not known

10 36%

Problems reported at the same time

13 46%

10 36%

9 32%

8 29%

8 29%

7 25%

7 25%

5 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause lymphadenopathy in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lymphadenopathy with similar medicines

Lymphadenopathy after Polysulfated Glycosaminoglycan 23 reports · 0.4% of its reports
Lymphadenopathy after Diphenhydramine 21 reports · 0.4% of its reports
Lymphadenopathy after Cephalexin 27 reports · 1.0% of its reports
Lymphadenopathy after Famotidine 21 reports · 0.8% of its reports
Lymphadenopathy after Ketoconazole 23 reports · 1.0% of its reports
Lymphadenopathy after Ampicillin 23 reports · 2.4% of its reports

All reported side effects of Cefpodoxime in dogs · Medicines most reported with lymphadenopathy