Decreased red blood cell count after Cefpodoxime in dogs

34 reports to the FDA describe decreased red blood cell count in dogs given Cefpodoxime. That is 0.8% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

34Reports

74%Marked serious

8.8%Recovered

32%Died or euthanised

26 daysTypical onset

How soon it started

Same day

1 3.7%

1–2 days

4 15%

3–7 days

0 0.0%

1–4 weeks

11 41%

Over a month

11 41%

How the animals did

Recovered

3 8.8%

Still unwell when reported

14 41%

Died

3 8.8%

Euthanised

8 24%

Not known

6 18%

Problems reported at the same time

19 56%

19 56%

15 44%

14 41%

13 38%

Decreased haemoglobin

13 38%

Decreased haematocrit

13 38%

Lethargy

12 35%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause decreased red blood cell count in dogs?: 34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 26 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased red blood cell count with similar medicines

Decreased red blood cell count after Polysulfated Glycosaminoglycan 30 reports · 0.5% of its reports
Decreased red blood cell count after Diphenhydramine 42 reports · 0.9% of its reports
Decreased red blood cell count after Butorphanol 23 reports · 0.5% of its reports
Decreased red blood cell count after Tramadol 20 reports · 0.5% of its reports
Decreased red blood cell count after Desoxycorticosterone Pivalate 28 reports · 0.8% of its reports
Decreased red blood cell count after Famotidine 44 reports · 1.7% of its reports
Decreased red blood cell count after Ketoconazole 24 reports · 1.1% of its reports
Decreased red blood cell count after Sucralfate 29 reports · 2.9% of its reports
Decreased red blood cell count after Ampicillin 30 reports · 3.1% of its reports
Decreased red blood cell count after Omeprazole 24 reports · 2.5% of its reports

All reported side effects of Cefpodoxime in dogs · Medicines most reported with decreased red blood cell count