Thrombocytosis after Carprofen (Rimadyl) in dogs

162 reports to the FDA describe thrombocytosis in dogs given Carprofen. That is 0.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

162Reports
48%Marked serious
5.6%Recovered
23%Died or euthanised
26 daysTypical onset
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How soon it started

Same day
5 6.3%
1–2 days
6 7.6%
3–7 days
11 14%
1–4 weeks
22 28%
Over a month
35 44%

How the animals did

Recovered
4 2.5%
Recovered with lasting effects
5 3.1%
Still unwell when reported
50 31%
Died
20 12%
Euthanised
18 11%
Not known
65 40%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
9
4–7 years
32
8–11 years
53
12+ years
59

About this medicine

Carprofen relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Rimadyl, Novox, Vetprofen. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Carprofen cause thrombocytosis in dogs?
162 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 26 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Thrombocytosis with similar medicines

All reported side effects of Carprofen in dogs · Medicines most reported with thrombocytosis