Lymphadenopathy after Carprofen (Rimadyl) in dogs

261 reports to the FDA describe lymphadenopathy in dogs given Carprofen. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

261Reports
25%Marked serious
1.9%Recovered
34%Died or euthanised
10 daysTypical onset
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How soon it started

Same day
6 9.4%
1–2 days
9 14%
3–7 days
12 19%
1–4 weeks
20 31%
Over a month
17 27%

How the animals did

Recovered
5 1.9%
Still unwell when reported
46 18%
Died
74 28%
Euthanised
16 6.1%
Not known
120 46%

Problems reported at the same time

Age of the animals

Under 1 year
10
1–3 years
26
4–7 years
74
8–11 years
97
12+ years
49

About this medicine

Carprofen relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Rimadyl, Novox, Vetprofen. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Carprofen cause lymphadenopathy in dogs?
261 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 10 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lymphadenopathy with similar medicines

All reported side effects of Carprofen in dogs · Medicines most reported with lymphadenopathy