Elevated globulins after Carprofen (Rimadyl) in dogs

373 reports to the FDA describe elevated globulins in dogs given Carprofen. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

373Reports
36%Marked serious
4.3%Recovered
29%Died or euthanised
10 daysTypical onset
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How soon it started

Same day
12 9.0%
1–2 days
16 12%
3–7 days
25 19%
1–4 weeks
45 34%
Over a month
35 26%

How the animals did

Recovered
14 3.8%
Recovered with lasting effects
2 0.5%
Still unwell when reported
94 25%
Died
86 23%
Euthanised
24 6.4%
Not known
153 41%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
33
4–7 years
110
8–11 years
138
12+ years
82

About this medicine

Carprofen relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Rimadyl, Novox, Vetprofen. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Carprofen cause elevated globulins in dogs?
373 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 10 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated globulins with similar medicines

All reported side effects of Carprofen in dogs · Medicines most reported with elevated globulins