Milbemycin Oxime + Spinosad (Trifexis) side effects in Springer Spaniels

151 FDA reports involve Milbemycin Oxime + Spinosad in a Springer Spaniel. These are the problems they describe.

Vomiting
63 42%
Didn't work as expected
23 15%
Didn't stop fleas
19 13%
Didn't prevent heartworm
18 12%
Lethargy
13 8.6%
Seizures
9 6.0%
Didn't stop worms
8 5.3%
Drug dose omission
7 4.6%
Wobbliness (ataxia)
7 4.6%
Diarrhea
7 4.6%
Death
7 4.6%
Itching
6 4.0%

All reports for Milbemycin Oxime + Spinosad in dogs