Milbemycin Oxime + Spinosad (Trifexis) side effects in Springer English Spaniels

213 FDA reports involve Milbemycin Oxime + Spinosad in a Springer English Spaniel. These are the problems they describe.

Vomiting
105 49%
Didn't work as expected
39 18%
Lethargy
37 17%
Didn't stop fleas
24 11%
Didn't stop worms
20 9.4%
Diarrhea
18 8.5%
Didn't prevent heartworm
16 7.5%
Itching
15 7.0%
Loss of appetite
13 6.1%
Behaviour change
10 4.7%
Seizures
8 3.8%
Tremors
6 2.8%

All reports for Milbemycin Oxime + Spinosad in dogs