Milbemycin Oxime + Spinosad (Trifexis) side effects in Shiba Inus

280 FDA reports involve Milbemycin Oxime + Spinosad in a Shiba Inu. These are the problems they describe.

Vomiting
128 46%
Lethargy
92 33%
Tremors
37 13%
Diarrhea
24 8.6%
Behaviour change
22 7.9%
Loss of appetite
21 7.5%
Wobbliness (ataxia)
19 6.8%
Didn't work as expected
17 6.1%
Seizures
17 6.1%
Itching
14 5.0%
Disorientation
14 5.0%
Didn't stop fleas
12 4.3%

All reports for Milbemycin Oxime + Spinosad in dogs