Milbemycin Oxime + Spinosad (Trifexis) side effects in Shepherds

104 FDA reports involve Milbemycin Oxime + Spinosad in a Shepherd. These are the problems they describe.

Vomiting
56 54%
Didn't work as expected
14 13%
Lethargy
14 13%
Loss of appetite
8 7.7%
Didn't stop worms
8 7.7%
Didn't prevent heartworm
7 6.7%
Itching
6 5.8%
Diarrhea
5 4.8%
Tremors
4 3.8%
Behaviour change
4 3.8%
Appetite loss
3 2.9%
Overdose
3 2.9%

All reports for Milbemycin Oxime + Spinosad in dogs