Milbemycin Oxime + Spinosad (Trifexis) side effects in Deutsche Dogge, Great Danes

656 FDA reports involve Milbemycin Oxime + Spinosad in a Deutsche Dogge, Great Dane. These are the problems they describe.

Vomiting
375 57%
Didn't prevent heartworm
78 12%
Didn't work as expected
73 11%
Diarrhea
48 7.3%
Lethargy
46 7.0%
Didn't stop fleas
35 5.3%
Loss of appetite
28 4.3%
Didn't stop worms
27 4.1%
Death
23 3.5%
Weight gain
21 3.2%
Weight loss
21 3.2%
Wobbliness (ataxia)
13 2.0%

All reports for Milbemycin Oxime + Spinosad in dogs