Milbemycin Oxime + Spinosad (Trifexis) side effects in Bullmastiffs

92 FDA reports involve Milbemycin Oxime + Spinosad in a Bullmastiff. These are the problems they describe.

Vomiting
62 67%
Lethargy
13 14%
Didn't work as expected
8 8.7%
Didn't prevent heartworm
7 7.6%
Loss of appetite
7 7.6%
Diarrhea
7 7.6%
Tremors
5 5.4%
Didn't stop fleas
4 4.3%
Breathing problems
4 4.3%
Didn't stop worms
4 4.3%
Itching
3 3.3%
Abnormal menace reflex test
2 2.2%

All reports for Milbemycin Oxime + Spinosad in dogs