Milbemycin Oxime + Spinosad (Trifexis) side effects in Border Collies

857 FDA reports involve Milbemycin Oxime + Spinosad in a Border Collie. These are the problems they describe.

Vomiting
363 42%
Didn't prevent heartworm
150 18%
Didn't work as expected
148 17%
Lethargy
86 10%
Didn't stop fleas
74 8.6%
Diarrhea
55 6.4%
Didn't stop worms
50 5.8%
Seizures
50 5.8%
Loss of appetite
37 4.3%
Itching
31 3.6%
Behaviour change
31 3.6%
Death
29 3.4%

All reports for Milbemycin Oxime + Spinosad in dogs