Hypercalcaemia after Bordetella Vaccine in dogs

29 reports to the FDA describe hypercalcaemia in dogs given Bordetella Vaccine. That is 0.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

29Reports

90%Marked serious

17%Recovered

38%Died or euthanised

9 daysTypical onset

How soon it started

Same day

2 11%

1–2 days

2 11%

3–7 days

5 26%

1–4 weeks

6 32%

Over a month

4 21%

How the animals did

Recovered

5 17%

Still unwell when reported

8 28%

Died

2 6.9%

Euthanised

9 31%

Not known

5 17%

Problems reported at the same time

19 66%

19 66%

16 55%

16 55%

16 55%

15 52%

12 41%

11 38%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause hypercalcaemia in dogs?: 29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypercalcaemia with similar medicines

Hypercalcaemia after Rabies Vaccine 30 reports · 0.3% of its reports
Hypercalcaemia after Leptospirosis Vaccine 34 reports · 0.4% of its reports
Hypercalcaemia after Distemper-parvo Vaccine 23 reports · 0.4% of its reports

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with hypercalcaemia