Decreased percentage of reticulocytes after Bordetella Vaccine in dogs

26 reports to the FDA describe decreased percentage of reticulocytes in dogs given Bordetella Vaccine. That is 0.3% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports
92%Marked serious
19%Recovered
38%Died or euthanised
56 daysTypical onset
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How soon it started

Same day
2 9.1%
1–2 days
3 14%
3–7 days
1 4.5%
1–4 weeks
4 18%
Over a month
12 55%

How the animals did

Recovered
5 19%
Still unwell when reported
8 31%
Died
1 3.8%
Euthanised
9 35%
Not known
3 12%

Problems reported at the same time

Blood problems
20 77%
Loss of appetite
18 69%
Lethargy
17 65%
Liver problems
16 62%
Neutrophilia
13 50%
Kidney problems
11 42%
Diarrhea
10 38%
Monocytosis
10 38%

Age of the animals

Under 1 year
2
1–3 years
10
4–7 years
5
8–11 years
5
12+ years
2

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause decreased percentage of reticulocytes in dogs?
26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 56 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased percentage of reticulocytes with similar medicines

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with decreased percentage of reticulocytes