Otorrhoea after Betamethasone + Florfenicol + Terbinafine in dogs

The FDA has received 31 reports of otorrhoea in dogs after Betamethasone + Florfenicol + Terbinafine. That is 1.3% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

31Reports

13%Marked serious

3.2%Recovered

0.0%Died or euthanised

18 daysTypical onset

How soon it started

Same day

4 17%

1–2 days

0 0.0%

3–7 days

3 13%

1–4 weeks

7 29%

Over a month

10 42%

How the animals did

Recovered

1 3.2%

Still unwell when reported

6 19%

Not known

24 77%

Problems reported at the same time

Didn't work as expected

17 55%

Head shake - ear disorder

6 19%

Skin redness

3 9.7%

Ear pain

3 9.7%

Itching

3 9.7%

Licking

2 6.5%

Skin inflammation

2 6.5%

Culture/titer data abnormal

2 6.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Betamethasone + Florfenicol + Terbinafine cause otorrhoea in dogs?: 31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 18 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Otorrhoea with similar medicines

Otorrhoea after Florfenicol + Mometasone + Terbinafine 115 reports · 3.2% of its reports
Otorrhoea after Ketoconazole 29 reports · 1.3% of its reports

All reported side effects of Betamethasone + Florfenicol + Terbinafine in dogs · Medicines most reported with otorrhoea