Ear pain after Betamethasone + Florfenicol + Terbinafine in dogs

The FDA has received 82 reports of ear pain in dogs after Betamethasone + Florfenicol + Terbinafine. That is 3.4% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

82Reports

35%Marked serious

16%Recovered

2.4%Died or euthanised

9 daysTypical onset

How soon it started

Same day

5 8.5%

1–2 days

8 14%

3–7 days

14 24%

1–4 weeks

18 31%

Over a month

14 24%

How the animals did

Recovered

12 15%

Recovered with lasting effects

1 1.2%

Still unwell when reported

26 32%

Euthanised

2 2.4%

Not known

41 50%

Problems reported at the same time

Didn't work as expected

38 46%

Ear discharge

34 41%

Skin redness

16 20%

Head shake - ear disorder

16 20%

14 17%

14 17%

11 13%

11 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Betamethasone + Florfenicol + Terbinafine cause ear pain in dogs?: 82 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Ear pain with similar medicines

Ear pain after Florfenicol + Mometasone + Terbinafine 143 reports · 4.0% of its reports
Ear pain after Genta Momet Clotrim 34 reports · 1.5% of its reports
Ear pain after Ketoconazole 41 reports · 1.8% of its reports

All reported side effects of Betamethasone + Florfenicol + Terbinafine in dogs · Medicines most reported with ear pain