Unable to rise after Bedinvetmab (Librela) in dogs

The FDA has received 269 reports of unable to rise in dogs after Bedinvetmab. That is 1.4% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

269Reports

85%Marked serious

7.4%Recovered

45%Died or euthanised

7 daysTypical onset

How soon it started

Same day

46 21%

1–2 days

42 19%

3–7 days

30 13%

1–4 weeks

36 16%

Over a month

69 31%

How the animals did

Recovered

20 7.4%

Still unwell when reported

112 42%

Died

30 11%

Euthanised

92 34%

Not known

15 5.6%

Problems reported at the same time

119 44%

76 28%

71 26%

69 26%

50 19%

49 18%

34 13%

33 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

100

12+ years

150

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause unable to rise in dogs?: 269 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with unable to rise