Paralysis after Bedinvetmab (Librela) in dogs

The FDA has received 210 reports of paralysis in dogs after Bedinvetmab. That is 1.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

210Reports

98%Marked serious

3.8%Recovered

65%Died or euthanised

3 daysTypical onset

How soon it started

Same day

46 25%

1–2 days

46 25%

3–7 days

23 12%

1–4 weeks

32 17%

Over a month

40 21%

How the animals did

Recovered

8 3.8%

Still unwell when reported

36 17%

Died

35 17%

Euthanised

102 49%

Not known

29 14%

Problems reported at the same time

137 65%

46 22%

38 18%

35 17%

33 16%

31 15%

29 14%

27 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

110

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause paralysis in dogs?: 210 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with paralysis