Inappropriate defecation after Bedinvetmab (Librela) in dogs

156 reports to the FDA describe inappropriate defecation in dogs given Bedinvetmab. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

156Reports
67%Marked serious
11%Recovered
26%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
35 26%
1–2 days
21 16%
3–7 days
21 16%
1–4 weeks
21 16%
Over a month
36 27%

How the animals did

Recovered
17 11%
Still unwell when reported
78 50%
Died
14 9.0%
Euthanised
26 17%
Not known
21 13%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
14
8–11 years
29
12+ years
110

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause inappropriate defecation in dogs?
156 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Inappropriate defecation with similar medicines

All reported side effects of Bedinvetmab in dogs · Medicines most reported with inappropriate defecation