Faecal incontinence after Bedinvetmab (Librela) in dogs

The FDA has received 403 reports of faecal incontinence in dogs after Bedinvetmab. That is 2.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

403Reports

65%Marked serious

9.2%Recovered

28%Died or euthanised

10 daysTypical onset

How soon it started

Same day

66 18%

1–2 days

49 14%

3–7 days

51 14%

1–4 weeks

73 20%

Over a month

119 33%

How the animals did

Recovered

34 8.4%

Recovered with lasting effects

3 0.7%

Still unwell when reported

205 51%

Died

28 6.9%

Euthanised

86 21%

Not known

47 12%

Problems reported at the same time

164 41%

114 28%

85 21%

84 21%

81 20%

67 17%

57 14%

48 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

131

12+ years

239

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause faecal incontinence in dogs?: 403 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Faecal incontinence with similar medicines

Faecal incontinence after Lokivetmab (Cytopoint) 24 reports · 0.4% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with faecal incontinence