Swollen limb after Atipamezole in dogs

The FDA has received 46 reports of swollen limb in dogs after Atipamezole. That is 1.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

46Reports

46%Marked serious

13%Recovered

15%Died or euthanised

4 daysTypical onset

How soon it started

Same day

8 20%

1–2 days

9 22%

3–7 days

9 22%

1–4 weeks

8 20%

Over a month

7 17%

How the animals did

Recovered

6 13%

Still unwell when reported

7 15%

Died

2 4.3%

Euthanised

5 11%

Not known

26 57%

Problems reported at the same time

Injection site reaction

33 72%

31 67%

20 43%

18 39%

18 39%

14 30%

Limb non-weight bearing

12 26%

Didn't work as expected

12 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Atipamezole cause swollen limb in dogs?: 46 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swollen limb with similar medicines

Swollen limb after Diphenhydramine 79 reports · 1.7% of its reports
Swollen limb after Butorphanol 83 reports · 1.9% of its reports
Swollen limb after Propofol 26 reports · 0.8% of its reports
Swollen limb after Famotidine 65 reports · 2.5% of its reports
Swollen limb after Tigilanol Tiglate 236 reports · 12% of its reports

All reported side effects of Atipamezole in dogs · Medicines most reported with swollen limb