Abnormal radiograph finding after Alfaxalone in dogs

The FDA has received 21 reports of abnormal radiograph finding in dogs after Alfaxalone. That is 4.2% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

21Reports

90%Marked serious

14%Recovered

19%Died or euthanised

3 daysTypical onset

How soon it started

Same day

5 25%

1–2 days

3 15%

3–7 days

10 50%

1–4 weeks

2 10%

Over a month

0 0.0%

How the animals did

Recovered

2 9.5%

Recovered with lasting effects

1 4.8%

Still unwell when reported

12 57%

Died

3 14%

Euthanised

1 4.8%

Not known

2 9.5%

Problems reported at the same time

Loss of appetite

12 57%

Vomiting

12 57%

Lethargy

10 48%

Didn't work as expected

10 48%

Neutrophilia

7 33%

Liver problems

7 33%

Monocytosis

7 33%

Kidney problems

6 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Alfaxalone cause abnormal radiograph finding in dogs?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal radiograph finding with similar medicines

Abnormal radiograph finding after Melarsomine (Immiticide) 344 reports · 1.5% of its reports
Abnormal radiograph finding after Polysulfated Glycosaminoglycan 155 reports · 2.8% of its reports
Abnormal radiograph finding after Diphenhydramine 149 reports · 3.2% of its reports
Abnormal radiograph finding after Butorphanol 138 reports · 3.1% of its reports
Abnormal radiograph finding after Cefpodoxime 120 reports · 3.0% of its reports
Abnormal radiograph finding after Tramadol 201 reports · 5.3% of its reports
Abnormal radiograph finding after Florfenicol + Mometasone + Terbinafine 31 reports · 0.9% of its reports
Abnormal radiograph finding after Desoxycorticosterone Pivalate 49 reports · 1.5% of its reports
Abnormal radiograph finding after Propofol 75 reports · 2.4% of its reports
Abnormal radiograph finding after Dirlotapide 28 reports · 1.0% of its reports

All reported side effects of Alfaxalone in dogs · Medicines most reported with abnormal radiograph finding