Behaviour change after Vitamin B12 in cats

The FDA has received 43 reports of behaviour change in cats after Vitamin B12. That is 11% of all reports for this medicine, compared with 5.4% across reports for all cat medicines, so it is reported unusually often with this medicine.

43Reports
65%Marked serious
12%Recovered
30%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
12 30%
1–2 days
8 20%
3–7 days
5 13%
1–4 weeks
9 23%
Over a month
6 15%

How the animals did

Recovered
4 9.3%
Recovered with lasting effects
1 2.3%
Still unwell when reported
15 35%
Died
5 12%
Euthanised
8 19%
Not known
10 23%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
3
4–7 years
5
8–11 years
10
12+ years
23

About this medicine

Type: medicine.

Questions owners ask

Can Vitamin B12 cause behaviour change in cats?
43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Vitamin B12 in cats · Medicines most reported with behaviour change