Excessive thirst after Velagliflozin (Senvelgo) in cats

The FDA has received 158 reports of excessive thirst in cats after Velagliflozin. That is 3.3% of all reports for this medicine, compared with 1.0% across reports for all cat medicines, so it is reported unusually often with this medicine.

158Reports
18%Marked serious
3.8%Recovered
8.2%Died or euthanised
13 daysTypical onset
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How soon it started

Same day
12 8.5%
1–2 days
19 13%
3–7 days
32 23%
1–4 weeks
27 19%
Over a month
52 37%

How the animals did

Recovered
6 3.8%
Still unwell when reported
12 7.6%
Died
3 1.9%
Euthanised
10 6.3%
Not known
127 80%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
22
8–11 years
70
12+ years
60

About this medicine

Velagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Senvelgo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Velagliflozin cause excessive thirst in cats?
158 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 13 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive thirst with similar medicines

All reported side effects of Velagliflozin in cats · Medicines most reported with excessive thirst