Hyperphosphataemia after Robenacoxib (Onsior) in cats

The FDA has received 106 reports of hyperphosphataemia in cats after Robenacoxib. That is 3.2% of all reports for this medicine, compared with 1.0% across reports for all cat medicines, so it is reported unusually often with this medicine.

106Reports
92%Marked serious
9.4%Recovered
49%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
14 16%
1–2 days
39 43%
3–7 days
14 16%
1–4 weeks
12 13%
Over a month
11 12%

How the animals did

Recovered
10 9.4%
Still unwell when reported
28 26%
Died
13 12%
Euthanised
39 37%
Not known
16 15%

Problems reported at the same time

Age of the animals

Under 1 year
20
1–3 years
9
4–7 years
21
8–11 years
33
12+ years
23

About this medicine

Robenacoxib relieves pain and inflammation (short courses).

Products with this ingredient include Onsior. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Robenacoxib cause hyperphosphataemia in cats?
106 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

All reported side effects of Robenacoxib in cats · Medicines most reported with hyperphosphataemia