Liver problems after Robenacoxib (Onsior) in cats

202 reports to the FDA describe liver problems in cats given Robenacoxib. That is 6.2% of all reports for this medicine, compared with 2.8% across reports for all cat medicines, so it is reported unusually often with this medicine.

202Reports
80%Marked serious
14%Recovered
40%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
50 28%
1–2 days
57 32%
3–7 days
26 15%
1–4 weeks
24 13%
Over a month
21 12%

How the animals did

Recovered
28 14%
Recovered with lasting effects
1 0.5%
Still unwell when reported
61 30%
Died
28 14%
Euthanised
53 26%
Not known
31 15%

Problems reported at the same time

Age of the animals

Under 1 year
31
1–3 years
46
4–7 years
45
8–11 years
48
12+ years
29

About this medicine

Robenacoxib relieves pain and inflammation (short courses).

Products with this ingredient include Onsior. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Robenacoxib cause liver problems in cats?
202 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Robenacoxib in cats · Medicines most reported with liver problems