Didn't work as expected after Prednisolone in cats

181 reports to the FDA describe didn't work as expected in cats given Prednisolone. That is 15% of all reports for this medicine, compared with 8.7% across reports for all cat medicines, so it is reported unusually often with this medicine.

181Reports
41%Marked serious
12%Recovered
8.3%Died or euthanised
19 daysTypical onset
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How soon it started

Same day
18 14%
1–2 days
13 10%
3–7 days
12 9.2%
1–4 weeks
30 23%
Over a month
57 44%

How the animals did

Recovered
21 12%
Recovered with lasting effects
1 0.6%
Still unwell when reported
77 43%
Died
1 0.6%
Euthanised
14 7.7%
Not known
67 37%

Problems reported at the same time

Loss of appetite
45 25%
Vomiting
25 14%
Lethargy
23 13%
Weight loss
22 12%
Itching
22 12%
Skin rash or irritation
15 8.3%
Hair loss
15 8.3%
Death
15 8.3%

Age of the animals

Under 1 year
7
1–3 years
10
4–7 years
34
8–11 years
29
12+ years
95

About this medicine

Prednisolone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisolone cause didn't work as expected in cats?
181 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 19 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

All reported side effects of Prednisolone in cats · Medicines most reported with didn't work as expected