Prednisolone side effects in cats

1,234 reports sent to the FDA between 1996 and 2026 involve Prednisolone in cats. The most reported problems were loss of appetite, vomiting, lethargy. 53% were marked serious, and where it was recorded, signs eased after stopping the medicine in 71% of cases.

1,234Reports
53%Marked serious
2.7%Only medicine involved
19%Recovered
15%Died or euthanised
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About this medicine

Prednisolone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a cat still getting fleas or heartworm), not about a side effect.

Didn't stop fleas
16 1.3%
Didn't prevent heartworm
4 0.3%
Didn't stop mites
1 0.1%
Didn't stop worms
1 0.1%

How soon problems started

Same day
164 17%
1–2 days
127 13%
3–7 days
113 12%
1–4 weeks
219 23%
Over a month
327 34%

Time from the first dose to the first sign, where both dates were reported (950 reports).

How the animals did

Recovered
228 18%
Recovered with lasting effects
12 1.0%
Still unwell when reported
494 40%
Died
75 6.1%
Euthanised
113 9.2%
Not known
312 25%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other corticosteroids for cats