Death after Ondansetron in cats

The FDA has received 48 reports of death in cats after Ondansetron. That is 22% of all reports for this medicine, compared with 8.9% across reports for all cat medicines, so it is reported unusually often with this medicine.

48Reports
98%Marked serious
0.0%Recovered
100%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
11 25%
1–2 days
12 27%
3–7 days
3 6.8%
1–4 weeks
8 18%
Over a month
10 23%

How the animals did

Died
13 27%
Euthanised
35 73%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
4
4–7 years
8
8–11 years
11
12+ years
21

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause death in cats?
48 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Ondansetron in cats · Medicines most reported with death