Application site reaction after Methylprednisolone in cats

The FDA has received 101 reports of application site reaction in cats after Methylprednisolone. That is 6.3% of all reports for this medicine, compared with 8.1% across reports for all cat medicines.

101Reports

50%Marked serious

18%Recovered

3.0%Died or euthanised

3 daysTypical onset

How soon it started

Same day

14 16%

1–2 days

27 32%

3–7 days

17 20%

1–4 weeks

21 25%

Over a month

6 7.1%

How the animals did

Recovered

18 18%

Still unwell when reported

43 43%

Euthanised

3 3.0%

Not known

37 37%

Problems reported at the same time

79 78%

43 43%

25 25%

18 18%

Skin rash or irritation

15 15%

Lethargy

13 13%

Didn't work as expected

11 11%

Skin scab

10 9.9%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Methylprednisolone cause application site reaction in cats?: 101 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Application site reaction with similar medicines

Application site reaction after Ketamine 38 reports · 1.2% of its reports
Application site reaction after Butorphanol 30 reports · 1.3% of its reports
Application site reaction after Isoflurane 45 reports · 2.2% of its reports
Application site reaction after Propofol 30 reports · 2.6% of its reports
Application site reaction after Spinetoram 24 reports · 9.2% of its reports
Application site reaction after Neomycin + Triamcinolone 31 reports · 22% of its reports

All reported side effects of Methylprednisolone in cats · Medicines most reported with application site reaction