Monocytosis after Insulin in cats

The FDA has received 25 reports of monocytosis in cats after Insulin. That is 0.7% of all reports for this medicine, compared with 0.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

25Reports

84%Marked serious

4.0%Recovered

20%Died or euthanised

49 daysTypical onset

How soon it started

Same day

3 20%

1–2 days

3 20%

3–7 days

0 0.0%

1–4 weeks

0 0.0%

Over a month

9 60%

How the animals did

Recovered with lasting effects

1 4.0%

Still unwell when reported

10 40%

Euthanised

5 20%

Not known

9 36%

Problems reported at the same time

14 56%

12 48%

12 48%

12 48%

11 44%

10 40%

10 40%

9 36%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause monocytosis in cats?: 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 49 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Monocytosis with similar medicines

Monocytosis after Velagliflozin (Senvelgo) 66 reports · 1.4% of its reports
Monocytosis after Bexagliflozin (Bexacat) 30 reports · 0.7% of its reports

All reported side effects of Insulin in cats · Medicines most reported with monocytosis