Death after Imidacloprid + Pyriproxyfen in cats

29 reports to the FDA describe death in cats given Imidacloprid + Pyriproxyfen. That is 4.4% of all reports for this medicine, compared with 8.9% across reports for all cat medicines, so it is reported less often than average with this medicine.

29Reports
100%Marked serious
0.0%Recovered
100%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
1 5.9%
1–2 days
6 35%
3–7 days
2 12%
1–4 weeks
4 24%
Over a month
4 24%

How the animals did

Died
17 59%
Euthanised
12 41%

Problems reported at the same time

Dehydration
5 17%
Hypothermia
5 17%
Wobbliness (ataxia)
4 14%

Age of the animals

Under 1 year
1
1–3 years
9
4–7 years
3
8–11 years
6
12+ years
6

About this medicine

Imidacloprid kills fleas (spot-on or collar).

Questions owners ask

Can Imidacloprid + Pyriproxyfen cause death in cats?
29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Imidacloprid + Pyriproxyfen in cats · Medicines most reported with death