Hyperphosphataemia after Frunevetmab (Solensia) in cats

90 reports to the FDA describe hyperphosphataemia in cats given Frunevetmab. That is 1.1% of all reports for this medicine, compared with 1.0% across reports for all cat medicines.

90Reports

88%Marked serious

2.2%Recovered

39%Died or euthanised

23 daysTypical onset

How soon it started

Same day

10 13%

1–2 days

10 13%

3–7 days

8 10%

1–4 weeks

19 24%

Over a month

32 41%

How the animals did

Recovered

2 2.2%

Still unwell when reported

47 52%

Died

3 3.3%

Euthanised

32 36%

Not known

6 6.7%

Problems reported at the same time

86 96%

43 48%

35 39%

30 33%

29 32%

Elevated symmetrical dimethylarginine (sdma)

28 31%

Vomiting

22 24%

Blood problems

19 21%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Frunevetmab reduces osteoarthritis pain in cats (monthly injection).

Products with this ingredient include Solensia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Frunevetmab cause hyperphosphataemia in cats?: 90 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 23 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Frunevetmab in cats · Medicines most reported with hyperphosphataemia