Vomiting after Dexmedetomidine (Dexdomitor) in cats

The FDA has received 164 reports of vomiting in cats after Dexmedetomidine. That is 6.2% of all reports for this medicine, compared with 18% across reports for all cat medicines, so it is reported less often than average with this medicine.

164Reports

45%Marked serious

34%Recovered

21%Died or euthanised

Same dayTypical onset

How soon it started

Same day

64 59%

1–2 days

16 15%

3–7 days

14 13%

1–4 weeks

6 5.6%

Over a month

8 7.4%

How the animals did

Recovered

56 34%

Still unwell when reported

24 15%

Died

21 13%

Euthanised

14 8.5%

Not known

49 30%

Problems reported at the same time

Loss of appetite

37 23%

Death

30 18%

Lethargy

28 17%

Didn't work as expected

26 16%

20 12%

20 12%

12 7.3%

12 7.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause vomiting in cats?: 164 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

Vomiting after Buprenorphine 266 reports · 4.8% of its reports

All reported side effects of Dexmedetomidine in cats · Medicines most reported with vomiting