Dehydration after Dexmedetomidine (Dexdomitor) in cats

The FDA has received 59 reports of dehydration in cats after Dexmedetomidine. That is 2.2% of all reports for this medicine, compared with 2.0% across reports for all cat medicines.

59Reports

63%Marked serious

14%Recovered

25%Died or euthanised

1 daysTypical onset

How soon it started

Same day

18 38%

1–2 days

16 33%

3–7 days

9 19%

1–4 weeks

3 6.3%

Over a month

2 4.2%

How the animals did

Recovered

8 14%

Still unwell when reported

21 36%

Died

6 10%

Euthanised

9 15%

Not known

15 25%

Problems reported at the same time

40 68%

30 51%

19 32%

15 25%

13 22%

13 22%

12 20%

11 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause dehydration in cats?: 59 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Buprenorphine 187 reports · 3.3% of its reports

All reported side effects of Dexmedetomidine in cats · Medicines most reported with dehydration