Vocalising after Dexmedetomidine (Dexdomitor) in cats

The FDA has received 100 reports of vocalising in cats after Dexmedetomidine. That is 3.8% of all reports for this medicine, compared with 3.1% across reports for all cat medicines.

100Reports

48%Marked serious

17%Recovered

29%Died or euthanised

Same dayTypical onset

How soon it started

Same day

57 68%

1–2 days

16 19%

3–7 days

4 4.8%

1–4 weeks

5 6.0%

Over a month

2 2.4%

How the animals did

Recovered

17 17%

Still unwell when reported

34 34%

Died

24 24%

Euthanised

5 5.0%

Not known

20 20%

Problems reported at the same time

34 34%

29 29%

26 26%

26 26%

18 18%

18 18%

17 17%

15 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause vocalising in cats?: 100 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

Vocalising after Buprenorphine 223 reports · 4.0% of its reports

All reported side effects of Dexmedetomidine in cats · Medicines most reported with vocalising