Underdose after Cyclosporine (Atopica) in cats

The FDA has received 20 reports of underdose in cats after Cyclosporine. That is 0.7% of all reports for this medicine, compared with 0.7% across reports for all cat medicines.

20Reports

15%Marked serious

35%Recovered

5.0%Died or euthanised

18 daysTypical onset

How soon it started

Same day

8 42%

1–2 days

1 5.3%

3–7 days

0 0.0%

1–4 weeks

1 5.3%

Over a month

9 47%

How the animals did

Recovered

7 35%

Still unwell when reported

1 5.0%

Euthanised

1 5.0%

Not known

11 55%

Problems reported at the same time

8 40%

4 20%

4 20%

3 15%

2 10%

2 10%

Didn't work as expected

2 10%

Eye disorder (for photophobia see 'neurological')

2 10%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause underdose in cats?: 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 18 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Cyclosporine in cats · Medicines most reported with underdose