Didn't work as expected after Cyclosporine (Atopica) in cats

The FDA has received 389 reports of didn't work as expected in cats after Cyclosporine. That is 13% of all reports for this medicine, compared with 8.7% across reports for all cat medicines.

389Reports

24%Marked serious

4.4%Recovered

2.8%Died or euthanised

51 daysTypical onset

How soon it started

Same day

38 14%

1–2 days

3 1.1%

3–7 days

11 4.0%

1–4 weeks

50 18%

Over a month

173 63%

How the animals did

Recovered

13 3.3%

Recovered with lasting effects

4 1.0%

Still unwell when reported

87 22%

Died

3 0.8%

Euthanised

8 2.1%

Not known

274 70%

Problems reported at the same time

50 13%

36 9.3%

32 8.2%

30 7.7%

25 6.4%

23 5.9%

19 4.9%

16 4.1%

Age of the animals

Under 1 year

1–3 years

4–7 years

114

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause didn't work as expected in cats?: 389 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 51 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

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