Lethargy after Clomipramine (Clomicalm) in cats

35 reports to the FDA describe lethargy in cats given Clomipramine. That is 28% of all reports for this medicine, compared with 14% across reports for all cat medicines, so it is reported unusually often with this medicine.

35Reports
8.6%Marked serious
11%Recovered
5.7%Died or euthanised
–Typical onset
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How the animals did

Recovered
3 8.6%
Recovered with lasting effects
1 2.9%
Still unwell when reported
1 2.9%
Died
2 5.7%
Not known
28 80%

Problems reported at the same time

Vomiting
7 20%
Liver problems
5 14%
Weight loss
4 11%
Kidney problems
3 8.6%
Dehydration
3 8.6%

Age of the animals

Under 1 year
2
1–3 years
4
4–7 years
8
8–11 years
10
12+ years
10

About this medicine

Clomipramine treats separation anxiety.

Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Clomipramine cause lethargy in cats?
35 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Clomipramine in cats · Medicines most reported with lethargy