Clomipramine (Clomicalm) side effects in cats

123 reports sent to the FDA between 1999 and 2026 involve Clomipramine in cats. The most reported problems were lethargy, loss of appetite, eye or vision problems. 20% were marked serious, and where it was recorded, signs eased after stopping the medicine in 25% of cases.

123Reports
20%Marked serious
85%Only medicine involved
11%Recovered
8.1%Died or euthanised
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About this medicine

Clomipramine treats separation anxiety.

Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Most reported side effects

35 28%
Behaviour change
14 11%
Liver problems
13 11%
Vomiting
12 9.8%
Vocalising
11 8.9%
Urinary tract disorder
11 8.9%
Constipation
10 8.1%
Weight loss
10 8.1%
Tachycardia
9 7.3%
Disorientation
8 6.5%
Kidney problems
8 6.5%
Urinary retention
8 6.5%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a cat still getting fleas or heartworm), not about a side effect.

Didn't work as expected
8 6.5%

How soon problems started

Same day
6 22%
1–2 days
4 15%
3–7 days
3 11%
1–4 weeks
3 11%
Over a month
11 41%

Time from the first dose to the first sign, where both dates were reported (27 reports).

How the animals did

Recovered
13 11%
Recovered with lasting effects
1 0.8%
Still unwell when reported
12 9.8%
Died
6 4.9%
Euthanised
4 3.3%
Not known
87 71%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other behaviour or anxiety medicines for cats