Elevated temperature after Buprenorphine in cats

208 reports to the FDA describe elevated temperature in cats given Buprenorphine. That is 3.7% of all reports for this medicine, compared with 0.4% across reports for all cat medicines, so it is reported unusually often with this medicine.

208Reports
28%Marked serious
42%Recovered
5.8%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
130 68%
1–2 days
45 24%
3–7 days
10 5.2%
1–4 weeks
3 1.6%
Over a month
3 1.6%

How the animals did

Recovered
87 42%
Still unwell when reported
71 34%
Died
4 1.9%
Euthanised
8 3.8%
Not known
38 18%

Problems reported at the same time

Age of the animals

Under 1 year
79
1–3 years
45
4–7 years
29
8–11 years
26
12+ years
10

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause elevated temperature in cats?
208 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated temperature with similar medicines

All reported side effects of Buprenorphine in cats · Medicines most reported with elevated temperature