Elevated amylase after Buprenorphine in cats

The FDA has received 22 reports of elevated amylase in cats after Buprenorphine. That is 0.4% of all reports for this medicine, compared with 0.4% across reports for all cat medicines.

22Reports

82%Marked serious

23%Recovered

45%Died or euthanised

1 daysTypical onset

How soon it started

Same day

7 35%

1–2 days

5 25%

3–7 days

5 25%

1–4 weeks

1 5.0%

Over a month

2 10%

How the animals did

Recovered

5 23%

Still unwell when reported

3 14%

Died

5 23%

Euthanised

5 23%

Not known

4 18%

Problems reported at the same time

14 64%

13 59%

12 55%

10 45%

9 41%

8 36%

8 36%

Abnormal radiograph finding

8 36%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause elevated amylase in cats?: 22 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Buprenorphine in cats · Medicines most reported with elevated amylase