Adipsia after Buprenorphine in cats

The FDA has received 73 reports of adipsia in cats after Buprenorphine. That is 1.3% of all reports for this medicine, compared with 0.9% across reports for all cat medicines.

73Reports

53%Marked serious

27%Recovered

23%Died or euthanised

1 daysTypical onset

How soon it started

Same day

23 35%

1–2 days

27 42%

3–7 days

9 14%

1–4 weeks

3 4.6%

Over a month

3 4.6%

How the animals did

Recovered

20 27%

Still unwell when reported

23 32%

Died

9 12%

Euthanised

8 11%

Not known

13 18%

Problems reported at the same time

67 92%

24 33%

21 29%

17 23%

16 22%

16 22%

Restlessness or agitation

13 18%

Fever

12 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause adipsia in cats?: 73 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Adipsia with similar medicines

Adipsia after Dexmedetomidine (Dexdomitor) 25 reports · 1.0% of its reports

All reported side effects of Buprenorphine in cats · Medicines most reported with adipsia