Laminitis after Pergolide in horses

The FDA has received 57 reports of laminitis in horses after Pergolide. That is 4.6% of all reports for this medicine, compared with 1.4% across reports for all horse medicines, so it is reported unusually often with this medicine.

57Reports

56%Marked serious

25%Recovered

18%Died or euthanised

11 daysTypical onset

How soon it started

Same day

7 20%

1–2 days

5 14%

3–7 days

2 5.7%

1–4 weeks

8 23%

Over a month

13 37%

How the animals did

Recovered

12 21%

Recovered with lasting effects

2 3.5%

Still unwell when reported

10 18%

Died

3 5.3%

Euthanised

7 12%

Not known

23 40%

Problems reported at the same time

10 18%

9 16%

7 12%

6 11%

5 8.8%

5 8.8%

Didn't work as expected

4 7.0%

Abnormal radiograph finding

4 7.0%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Pergolide cause laminitis in horses?: 57 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Laminitis with similar medicines

Laminitis after Ceftiofur 28 reports · 2.3% of its reports
Laminitis after Triamcinolone 20 reports · 14% of its reports

All reported side effects of Pergolide in horses · Medicines most reported with laminitis