Dexamethasone side effects in horses

61 reports sent to the FDA between 1996 and 2026 involve Dexamethasone in horses. The most reported problems were swelling, allergic reaction, injection site reaction. 49% were marked serious, and where it was recorded, signs eased after stopping the medicine in 0% of cases.

61Reports
49%Marked serious
26%Only medicine involved
20%Recovered
33%Died or euthanised
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About this medicine

Dexamethasone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Most reported side effects

Swelling
14 23%
Allergic reaction
13 21%
Injection site reaction
12 20%
Loss of appetite
9 15%
Lethargy
7 11%
Laminitis
6 9.8%
Wobbliness (ataxia)
6 9.8%
Liver problems
5 8.2%
Colic
5 8.2%
Restlessness or agitation
5 8.2%
Diarrhea
5 8.2%
Fever
4 6.6%
Breathing problems
4 6.6%
Behaviour change
4 6.6%
Collapse
4 6.6%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a horse still getting fleas or heartworm), not about a side effect.

Didn't work as expected
2 3.3%

How soon problems started

Same day
12 32%
1–2 days
5 14%
3–7 days
6 16%
1–4 weeks
10 27%
Over a month
4 11%

Time from the first dose to the first sign, where both dates were reported (37 reports).

How the animals did

Recovered
11 18%
Recovered with lasting effects
1 1.6%
Still unwell when reported
8 13%
Died
11 18%
Euthanised
9 15%
Not known
21 34%

Breeds named most often

Popular breeds appear more often because there are more of them.