Decreased haematocrit after Verdinexor in dogs

27 reports to the FDA describe decreased haematocrit in dogs given Verdinexor. That is 6.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

27Reports
78%Marked serious
7.4%Recovered
44%Died or euthanised
16 daysTypical onset
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How soon it started

Same day
4 15%
1–2 days
0 0.0%
3–7 days
3 12%
1–4 weeks
12 46%
Over a month
7 27%

How the animals did

Recovered
1 3.7%
Recovered with lasting effects
1 3.7%
Still unwell when reported
3 11%
Died
3 11%
Euthanised
9 33%
Not known
10 37%

Problems reported at the same time

12 44%
Decreased red blood cell count
8 30%

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
7
8–11 years
11
12+ years
7

About this medicine

Type: medicine.

Questions owners ask

Can Verdinexor cause decreased haematocrit in dogs?
27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 16 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased haematocrit with similar medicines

All reported side effects of Verdinexor in dogs · Medicines most reported with decreased haematocrit