Hyperextension after Toceranib in dogs

28 reports to the FDA describe hyperextension in dogs given Toceranib. That is 2.6% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

28Reports

25%Marked serious

0.0%Recovered

11%Died or euthanised

31 daysTypical onset

How soon it started

Same day

5 31%

1–2 days

0 0.0%

3–7 days

1 6.3%

1–4 weeks

2 13%

Over a month

8 50%

How the animals did

Still unwell when reported

23 82%

Euthanised

3 11%

Not known

2 7.1%

Problems reported at the same time

Didn't work as expected

28 100%

Underdose

8 29%

Vomiting

5 18%

Diarrhea

5 18%

Drug dose administration interval too long

3 11%

Straining to defecate

3 11%

Lethargy

3 11%

Death

3 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Toceranib cause hyperextension in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 31 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperextension with similar medicines

Hyperextension after Dirlotapide 328 reports · 12% of its reports

All reported side effects of Toceranib in dogs · Medicines most reported with hyperextension