Didn't stop fleas after Premise Spray in dogs

The FDA has received 61 reports of didn't stop fleas in dogs after Premise Spray. That is 88% of all reports for this medicine, compared with 6.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

61Reports
0.0%Marked serious
1.6%Recovered
0.0%Died or euthanised
–Typical onset
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How the animals did

Recovered
1 1.6%
Still unwell when reported
2 3.3%
Not known
58 95%

Problems reported at the same time

Itching
3 4.9%
Drug dose administration interval too short
3 4.9%
Underdose
2 3.3%
Product label issues
2 3.3%
Didn't work as expected
2 3.3%
Product defect, general
2 3.3%
Product problem
1 1.6%
Overdose
1 1.6%

Age of the animals

Under 1 year
7
1–3 years
16
4–7 years
21
8–11 years
8
12+ years
5

About this medicine

Type: medicine.

Questions owners ask

Can Premise Spray cause didn't stop fleas in dogs?
61 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't stop fleas with similar medicines

All reported side effects of Premise Spray in dogs · Medicines most reported with didn't stop fleas