Pimobendan (Vetmedin) side effects in dogs

5,701 reports sent to the FDA between 2003 and 2026 involve Pimobendan in dogs. The most reported problems were vomiting, diarrhea, loss of appetite. 33% were marked serious, and where it was recorded, signs eased after stopping the medicine in 75% of cases.

5,701Reports
33%Marked serious
49%Only medicine involved
27%Recovered
14%Died or euthanised
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About this medicine

Pimobendan treats heart failure and some heart disease.

Products with this ingredient include Vetmedin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Most reported side effects

1,044 18%
903 16%
818 14%
427 7.5%
319 5.6%
261 4.6%
217 3.8%
177 3.1%
171 3.0%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop worms
12 0.2%
Didn't stop ticks
5 0.1%

How soon problems started

Same day
727 21%
1–2 days
435 12%
3–7 days
295 8.4%
1–4 weeks
547 16%
Over a month
1,520 43%

Time from the first dose to the first sign, where both dates were reported (3,524 reports).

How the animals did

Recovered
1,521 27%
Recovered with lasting effects
33 0.6%
Still unwell when reported
642 11%
Died
474 8.3%
Euthanised
297 5.2%
Not known
2,734 48%

Breeds named most often

Popular breeds appear more often because there are more of them.